Research

Mixed

Adopting a Mediterranean-style Step I diet (high in alpha-linolenic acid, fruits, vegetables, and fish) significantly reduces the risk of recurrent cardiovascular disease events compared to a standard Step I diet in post-myocardial infarction patients.

If you have had a heart attack, switch to a Mediterranean-style diet. Eat more bread, root/green vegetables, fish, and fruit daily. Replace red meat with poultry. Use margarine high in alpha-linolenic acid (like canola/vegetable oil blends) instead of butter/cream. This specific pattern has been shown to cut recurrent heart event risk by half to seventy percent compared to standard low-fat diets, even when cholesterol levels look similar.

ModerateSupportsMEDIUM confidence
subjects following the Mediterranean-style diet had a 50% to 70% lower risk of recurrent heart disease, as measured by 3 different combinations of outcome measures including (1) cardiac death and nonfatal heart attacks; (2) the preceding plus unstable angina, stroke, heart failure, and pulmonary or peripheral embolism; (3) all of these measures plus events that required hospitalization.
Penny M. Kris‐Etherton et al. · Circulation · 2001

Why this rating

It is a randomized controlled trial, but the study was stopped early due to efficacy, and there are methodological limitations regarding dietary assessment in the control group.

Source

Lyon Diet Heart Study

Penny M. Kris‐Etherton et al. · Circulation · 2001

DOI 10.1161/01.cir.103.13.1823

narrative_review · n=605Cited 402×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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