Hormonal
Plasma leptin concentrations are not affected by dietary fat content (ranging from 14% to 31% of energy) when body weight and adiposity are held constant.
If you are maintaining your current weight, changing the percentage of fat in your diet (whether you eat 14%, 23%, or 31% of calories from fat) will not change your leptin levels. Leptin is driven by how much body fat you have, not by the specific macronutrient ratio of your food, provided your weight remains stable.
Plasma leptin concentrations were not affected by varying dietary fat content (31%, 23%, and 14% of energy) when body weight was held constant on weight-maintaining diets.
Why this rating
Controlled clinical trial with sequential diet interventions and stable body weight measurements.
Source
Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: effects of dietary fat content and sustained weight loss.
Peter J. Havel et al. · The Journal of Clinical Endocrinology & Metabolism · 1996
DOI 10.1210/jcem.81.12.8954050
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- Overweight/obese women have higher plasma leptin levels per unit of adiposity (leptin/adiposity ratio) compared to normal weight women, and this ratio decreases significantly after sustained weight loss in the overweight/obese group.Good
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