Mixed
The Ketogenic Diet alters gut microbiota composition, increasing beneficial bacteria like Akkermansia and Parabacteriodes, which contributes to anti-seizure and anti-inflammatory effects.
Following a ketogenic diet changes your gut bacteria, increasing beneficial types like Akkermansia and reducing harmful ones. This shift is linked to reduced inflammation and seizure activity. You don't need to take probiotics; the diet itself drives these positive changes.
Mice that were fed a 4-day KD showed significant changes in gut bacterial composition, which was characterized by an increase in Akkermansia and Parabacteriodes populations that induced an anti-seizure effect in germ-free or antibiotic-treated mice.
Why this rating
Supported by multiple murine and human studies cited in the review, showing consistent shifts in specific bacterial genera.
Source
Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations
Huiyuan Zhu et al. · Signal Transduction and Targeted Therapy · 2022
DOI 10.1038/s41392-021-00831-w
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