Mixed
Longer duration of obesity is independently associated with increased all-cause and cause-specific mortality, with risk increasing significantly for every additional 2 years of obesity duration.
If you have been obese for a long time, your risk of dying from any cause, heart disease, or cancer is higher than someone who has never been obese, even if your current weight is normal. This risk accumulates over time. The best strategy is to achieve and maintain a healthy weight as early as possible to minimize the total years lived with obesity.
The adjusted hazard ratio (HR) for mortality increased as the number of years lived with obesity increased... For every additional 2 years of obesity, the HRs for all-cause, cardiovascular disease, cancer and other-cause mortality were 1.06 (95% CI 1.05–1.07), 1.07 (95% CI 1.05–1.08), 1.03 (95% CI 1.01–1.05) and 1.07 (95% CI 1.05–1.11), respectively.
Why this rating
Large prospective cohort study (Framingham) with long follow-up (up to 48 years) and rigorous statistical adjustment.
Source
The number of years lived with obesity and the risk of all-cause and cause-specific mortality
Asnawi Abdullah et al. · International Journal of Epidemiology · 2011
DOI 10.1093/ije/dyr018
Related findings · Mixed
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