Hormonal
Gut microbiota composition influences obesity risk through the production of short-chain fatty acids (SCFAs), where butyrate and propionate act as anti-obesogenic agents by improving insulin sensitivity and regulating appetite, while acetate acts as an obesogenic substrate for lipogenesis.
Your gut bacteria produce chemicals that directly affect your weight. Some byproducts (butyrate, propionate) help control hunger and fat storage, while others (acetate) can fuel fat creation. To support the beneficial byproducts, prioritize fiber-rich foods that feed the specific bacteria that produce them, rather than just focusing on calorie counting.
Out of these, butyrate and propionate are predominantly antiobesogenic... Unlike butyrate and propionate, acetate, which is substantially absorbed, shows more obesogenic potential, as it acts as a substrate for hepatic and adipocyte lipogenesis.
Why this rating
The paper is a review summarizing multiple animal and human studies, lacking a single primary clinical trial.
Source
New-found link between microbiota and obesity
Chandra Kanti Chakraborti · World Journal of Gastrointestinal Pathophysiology · 2015
DOI 10.4291/wjgp.v6.i4.110
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