Research

Mixed

Mushroom polysaccharides (specifically beta-glucans) act as prebiotics that modulate gut microbiota to attenuate obesity and hyperglycemia.

Incorporate medicinal mushrooms (like Shiitake, Maitake, or Reishi) into your diet to support gut health. Their beta-glucans are not fully digested but feed beneficial gut bacteria, which may help manage weight and blood sugar. While not a magic bullet, they are a safe, low-calorie functional food with biological activity.

ModerateSupportsMEDIUM confidence
The mechanisms of action involve the gut microbiota, meaning the polysaccharides act as prebiotics in the digestive system.
Mendel Friedman · Foods · 2016

Why this rating

The paper is a review of multiple studies (cells, rodents, humans) with varying quality; it highlights promising results but notes gaps in human clinical data.

Source

Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans

Mendel Friedman · Foods · 2016

DOI 10.3390/foods5040080

narrative_reviewCited 360×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

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