Energy balance
Short-term high-intensity swimming training significantly reduces infarct size and cellular damage (measured by CPK levels) in a rat model of myocardial ischemia, demonstrating a protective preconditioning effect against heart attack damage.
This finding is specific to a rat model of heart attack. For humans, regular exercise is generally known to improve cardiovascular health, but this specific protocol (3 hours/day of high-intensity swimming for 3 weeks in young rats) is not a recommended human prescription. Consult a physician before starting high-intensity regimens, especially if you have heart risk factors.
Morphological staining found that infarct sizes was lower in EXC (14.7 ± 0.3%) and IPC’s (17.6 ± 0.5%) than CON (26.2 ± 0.6%). CPK concentration in cardiac, kidney in EXC (0.80), IPC (0.92) were lower than CON (4.03) in blood exam. This result indicated there was lower cellular damage in EXC and IPC.
Why this rating
Animal study (rats) with small sample size (n=15 per group); results may not translate directly to human clinical outcomes.
Source
Skeletal muscle and resistance exercise training; the role of protein synthesis in recovery and remodeling
Chris McGlory et al. · Journal of Applied Physiology · 2016
DOI 10.1152/japplphysiol.00613.2016
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