Research
Micronutrients & recovery
Vitamin D3 supplementation significantly reduces cancer mortality by 16%, whereas Vitamin D2 does not show this benefit.
If you take Vitamin D for cancer prevention, ensure you are taking Vitamin D3, not D2. This review found a 16% reduction in cancer death risk with D3, but no such benefit with D2. D3 is also more effective at raising blood levels of Vitamin D.
GoodQualifiesMEDIUM confidence
Vitamin D supplementation statistically significantly reduced the risk of cancer death (0.84, 0.74 to 0.95, 0%)... benefit was only seen in participants receiving vitamin D3 supplementation not vitamin D2.
Why this rating
Based on subgroup analysis of a high-quality meta-analysis; the finding is statistically significant but specific to a subset of the population/intervention.
Source
Association between vitamin D supplementation and mortality: systematic review and meta-analysis
Yu Zhang et al. · BMJ · 2019
DOI 10.1136/bmj.l4673
Meta-analysis · 52 studiesCited 359×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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