Research
Hormonal
Specific gut bacteria, including Bacteroides fragilis (via Polysaccharide A) and Faecalibacterium prausnitzii, can enhance the efficacy of cancer immunotherapy (ICB) by modulating T-cell responses and reducing inflammation.
For cancer patients undergoing immunotherapy, maintaining gut health through a diverse, fiber-rich diet may support the efficacy of treatment. While specific NGPs like B. fragilis and F. prausnitzii show promise, they are not yet standard clinical interventions. Consult with oncology teams before making significant dietary changes.
ModerateSupportsMEDIUM confidence
B. fragilis polysaccharide A (PSA)... enrich a specific subset of anti-inflammatory memory CD4+FoxP3 T cells... systematic amelioration of inflammation related diseases such as... cancers
Why this rating
Review of clinical correlations and animal models; causal mechanisms in humans are still being elucidated.
Source
Next generation probiotics in disease amelioration
Chih‐Jung Chang et al. · Journal of Food and Drug Analysis · 2019
DOI 10.1016/j.jfda.2018.12.011
narrative_reviewCited 359×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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