Mixed
Computed tomography (CT) assessment of muscle mass and myosteatosis lacks standardization across studies, with significant variation in anatomic landmarks, thresholding values, and reporting of technical parameters like contrast use and slice thickness.
When interpreting or conducting CT-based muscle assessments, ensure strict adherence to standardized protocols regarding anatomic landmarks (e.g., L3), thresholding values, and reporting of technical parameters (contrast, slice thickness). Lack of standardization currently limits the ability to compare results across studies or clinics.
There is considerable variation in the CT approaches used for the assessment of muscle mass and myosteatosis. There is a need to develop consensus for CT-based evaluation of sarcopenia and myosteatosis.
Why this rating
Systematic review of 388 studies with low risk of bias for methodology review.
Source
Approaches to Assessment of Muscle Mass and Myosteatosis on Computed Tomography: A Systematic Review
Behrang Amini et al. · The Journals of Gerontology Series A · 2019
DOI 10.1093/gerona/glz034
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →