Research
Micronutrients & recovery
Magnesium supplementation (approx. 300-486 mg/day) can lower blood pressure and C-reactive protein (CRP) in specific clinical populations, such as those with hypertension or heart failure.
If you have hypertension or heart failure, discuss magnesium supplementation with your doctor. Studies suggest doses around 300-486 mg/day may help lower blood pressure and inflammation, but this is not effective for people with normal blood pressure.
GoodSupportsHIGH confidence
a recent review of 44 studies concluded that 486 mg magnesium/day... is necessary to achieve significant lowering of high blood pressure... In one study, CRP was significantly higher (and serum magnesium significantly lower) in patients admitted for heart failure versus those admitted for other causes; this study also showed oral magnesium of 300 mg/day given to heart failure patients raised both intracellular and serum magnesium while lowering serum CRP compared with control heart failure patients...
Why this rating
Based on a review of 44 studies and specific clinical trials, though results can be conflicting.
Source
Suboptimal magnesium status in the United States: are the health consequences underestimated?
Andrea Rosanoff et al. · Nutrition Reviews · 2012
DOI 10.1111/j.1753-4887.2011.00465.x
narrative_reviewCited 357×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Suboptimal magnesium status and a rising dietary calcium-to-magnesium ratio are associated with increased risk of type 2 diabetes, metabolic syndrome, and cardiovascular disease.Moderate
- Magnesium deficiency is mechanistically linked to cellular calcium activation, which drives inflammation, metabolic syndrome, and vascular calcification via TRPM channels.Moderate
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