Research
Micronutrients & recovery
Optimal selenium status for maximizing glutathione peroxidase (GPx) expression requires serum or plasma selenium concentrations between 90–100 μg/L.
To maximize the activity of glutathione peroxidase, an antioxidant enzyme, aim for a serum selenium level of 90–100 μg/L. This is a specific biomarker target that may require supplementation if your diet is low in selenium.
GoodSupportsHIGH confidence
GPx activity is commonly used as a marker for Se sufficiency in the body, where serum or plasma Se concentrations are believed to achieve maximum GPx expression at 90–100 μg/L
Why this rating
Cites specific studies (Duffield, Alfthan) establishing the threshold.
Source
A Review of Dietary Selenium Intake and Selenium Status in Europe and the Middle East
Rita Stoffaneller et al. · Nutrients · 2015
DOI 10.3390/nu7031494
systematic_reviewCited 354×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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