Micronutrients & recovery
Quercetin acts as a SIRT1 activator to mitigate aging-related diseases, including neurodegenerative disorders, by regulating oxidative stress, inflammation, and mitochondrial function.
Quercetin is a natural flavonoid found in foods like onions and grapes that may help protect against age-related brain and body decline by activating the SIRT1 protein. This activation helps reduce inflammation and oxidative stress. While animal studies show promise for conditions like Alzheimer's and Parkinson's, human clinical data is not provided here, so it should be viewed as a potential supportive supplement rather than a cure.
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging-related diseases. Sirtuin 1 (SIRT1)... is extensively explored as a potential therapeutic target for attenuating aging-induced disorders.
Why this rating
The paper is a review summarizing various in vitro and in vivo animal studies; no human clinical trials are detailed.
Source
Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism
Zhifu Cui et al. · Frontiers in Immunology · 2022
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