Research

Mixed

Supplementation with marine long-chain omega-3 fatty acids (EPA/DHA) reduces the risk of cardiovascular events, cardiac death, and coronary events in individuals with high cardiovascular risk.

If you are at high risk for cardiovascular disease, taking marine omega-3 supplements (EPA/DHA) in addition to your standard medical treatment can reduce your risk of heart events, heart-related death, and coronary issues. Aim for a daily intake consistent with clinical guidelines (often around 1g EPA/DHA for those with coronary disease), but consult your doctor to determine the right dose for your specific condition.

GoodSupportsHIGH confidence
We found an overall decrease of risk of suffering a cardiovascular event of any kind of 10 % (OR 0·90; [0·85– 0·96], p ¼ 0·001), a 9 % decrease of risk of cardiac death (OR 0·91; [0·83– 0·99]; p ¼ 0·03), a decrease of coronary events (fatal and non-fatal) of 18 % (OR 0·82; [0·75– 0·90]; p , 1 £ 1024)... marine omega-3 fatty acids are effective in preventing cardiovascular events, cardiac death and coronary events, especially in persons with high cardiovascular risk.
Javier Delgado‐Lista et al. · British Journal Of Nutrition · 2012

Why this rating

Systematic review of 21 randomized controlled trials with large sample sizes (45,000+ participants), though heterogeneity exists.

Source

Long chain omega-3 fatty acids and cardiovascular disease: a systematic review

Javier Delgado‐Lista et al. · British Journal Of Nutrition · 2012

DOI 10.1017/s0007114512001596

Meta-analysis · 21 studiesCited 347×
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DOI resolved against Crossref · corpus check 2026-06-10

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