Macro partitioning
Substituting 5% of energy from carbohydrates or fat with protein increases the risk of type 2 diabetes by approximately 30%, regardless of whether the displaced macronutrient is fat or carbs.
If you are trying to prevent diabetes, simply swapping carbohydrates for protein (e.g., eating more meat instead of bread) may actually increase your risk. The study suggests that the increase in protein itself, rather than the decrease in carbs or fat, drives this risk. Balance your protein intake rather than maximizing it at the expense of other macros.
Consuming 5 energy % from protein at the expense of 5 energy % from carbohydrates or fat increased diabetes risk by ~30%.
Why this rating
Prospective cohort with robust statistical modeling for isocaloric substitution.
Source
Dietary Intake of Total, Animal, and Vegetable Protein and Risk of Type 2 Diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-NL Study
Ivonne Sluijs et al. · Diabetes Care · 2009
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