Research
Hormonal
Lactobacillus rhamnosus CGMCC1.3724 supplementation reduces circulating leptin concentrations in obese women independently of fat mass loss.
This probiotic may help regulate hunger signals (leptin) in obese women, potentially making it easier to maintain a calorie deficit, independent of how much fat they actually lose.
GoodSupportsHIGH confidence
These differences remained significant when the values were corrected for the loss of fat mass between baseline and week 24, suggesting that LPR decreased plasma leptin concentrations independently of fat mass reduction.
Why this rating
Supported by the same RCT data; the independent effect is a statistical adjustment within the same robust study.
Source
Effect of<i>Lactobacillus rhamnosus</i>CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women
Marina Sánchez et al. · British Journal Of Nutrition · 2013
DOI 10.1017/s0007114513003875
rct · n=125Cited 339×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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