Research

Micronutrients & recovery

In older women, the use of multivitamins, vitamin B6, folic acid, magnesium, zinc, and copper is associated with an increased risk of total mortality.

If you are an older woman, be aware that taking multivitamins, vitamin B6, folic acid, magnesium, zinc, or copper might be linked to a higher risk of death. This study found that women who took these supplements had a slightly higher chance of dying during the follow-up period. You should discuss with your doctor whether you really need these supplements.

GoodRefutesHIGH confidence
the use of multivitamins (hazard ratio, 1.06; 95% CI, 1.02-1.10; absolute risk increase, 2.4%), vitamin B6 (1.10; 1.01-1.21; 4.1%), folic acid (1.15; 1.00-1.32; 5.9%), iron (1.10; 1.03-1.17; 3.9%), magnesium (1.08; 1.01-1.15; 3.6%), zinc (1.08; 1.01-1.15; 3.0%), and copper (1.45; 1.20-1.75; 18.0%) were associated with increased risk of total mortality when compared with corresponding nonuse.
Jaakko Mursu · Archives of Internal Medicine · 2011

Why this rating

Large longitudinal cohort study with extensive adjustment for confounders, though observational design prevents definitive causal proof.

Source

Dietary Supplements and Mortality Rate in Older Women

Jaakko Mursu · Archives of Internal Medicine · 2011

cohort · n=38772Cited 339×
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