Mixed
In patients with Nonalcoholic Steatohepatitis (NASH), improvement in hepatic steatosis (reduced intrahepatic triglyceride content) is associated with a specific shift in gut microbiota composition, characterized by a reduction in Firmicutes and an increase in Bacteroidetes.
If you have NASH, your gut bacteria composition is likely different from healthy individuals, specifically with lower levels of beneficial Firmicutes and higher Bacteroidetes. While taking probiotics alone did not significantly reduce liver fat in this study, the *shift* in your gut bacteria (more Bacteroidetes, less Firmicutes) correlates with better liver health. Focus on dietary patterns that support this microbial balance rather than relying on probiotic supplements alone.
Improvement in IHTG was associated with a reduction in the abundance of Firmicutes (R2 = 0.4820, P = 0.0028) and increase in Bacteroidetes (R2 = 0.4366, P = 0.0053).
Why this rating
Observational correlation within a small randomized trial (n=16); causality not established.
Source
Molecular Characterization of the Fecal Microbiota in Patients with Nonalcoholic Steatohepatitis – A Longitudinal Study
Vincent Wai‐Sun Wong et al. · PLoS ONE · 2013
DOI 10.1371/journal.pone.0062885
Related findings · Mixed
- Bariatric surgery (VSG and RYGB) is the most effective and sustainable treatment for obesity, producing marked and sustained weight loss that non-surgical interventions cannot match.Strong
- Severely protein-deficient diets (2–3% energy) induce lean body mass loss and metabolic imbalance, whereas adequate protein intake (0.66 g/kg/d minimum) is a prerequisite for maintaining muscle, bone, and physiological function.Strong
- For patients with Class III obesity (BMI >39.9 kg/m2), metabolic bariatric surgery (MBS) is significantly more effective than any currently approved medication, with BilioPancreatic Diversion (BPD) showing the highest estimated weight loss.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →