Research

Mixed

Higher leisure time physical activity is associated with a reduced risk of major adverse cardiovascular events (MACE) and all-cause mortality, whereas higher occupational physical activity is associated with increased risks of both outcomes.

Prioritize physical activity in your leisure time for heart health and longevity. Do not rely on your job's physical demands to protect your cardiovascular system, as high occupational activity may actually increase your risk of heart events and death. Aim for dynamic, conditioning-level exercise during free time, ensuring you have adequate recovery.

StrongQualifiesHIGH confidence
Higher leisure time physical activity associates with reduced MACE and all-cause mortality risk, while higher occupational physical activity associates with increased risks, independent of each other.
Andreas Holtermann et al. · European Heart Journal · 2021

Why this rating

Large prospective cohort study (N=104,046), long follow-up (median 10 years), rigorous multivariable adjustments, and sensitivity analyses.

Source

The physical activity paradox in cardiovascular disease and all-cause mortality: the contemporary Copenhagen General Population Study with 104 046 adults

Andreas Holtermann et al. · European Heart Journal · 2021

cohort · n=104046Cited 328×
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