Research
Hormonal
Visfatin (Nampt) promotes cancer cell survival and migration through inflammatory, metabolic, and antioxidant pathways, particularly in colorectal and ovarian cancers.
Visfatin is a molecule that increases with obesity and can promote cancer cell survival and spread, especially in colorectal and ovarian cancers. Reducing obesity may help lower visfatin levels, potentially slowing cancer progression.
ModerateSupportsMEDIUM confidence
Current studies propose that visfatin is involved in the development and pathophysiology of a number of different cancers... The relation of visfatin to colorectal cancer (CRC) is among the best characterized to date.
Why this rating
Supported by in vitro and animal studies, but human data is less comprehensive.
Source
Adipose tissue, obesity and adipokines: role in cancer promotion
Andrea Booth et al. · Hormone Molecular Biology and Clinical Investigation · 2015
DOI 10.1515/hmbci-2014-0037
narrative_reviewCited 325×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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