Research
Hormonal
Colonic SCFA mixtures increase plasma Peptide YY (PYY) concentrations, a satiety-stimulating hormone, in both fasting and postprandial states.
Eating fiber-rich foods stimulates the release of Peptide YY (PYY), a hormone that signals fullness to your brain. To manage appetite, ensure your diet includes sufficient fermentable fibers (found in vegetables, fruits, and whole grains) to support natural PYY production.
GoodSupportsHIGH confidence
In addition, all three SCFA mixtures increased fasting and postprandial plasma peptide YY (PYY) concentrations (P < 0.05).
Why this rating
Same high-quality RCT design as N1.
Source
Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial
Emanuel E. Canfora et al. · Scientific Reports · 2017
DOI 10.1038/s41598-017-02546-x
crossover · n=12Cited 319×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Colonic administration of short-chain fatty acid (SCFA) mixtures (high in acetate, propionate, or butyrate) increases fasting fat oxidation and resting energy expenditure in overweight/obese men.Good
- Colonic SCFA mixtures attenuate whole-body lipolysis, indicated by decreased fasting free glycerol concentrations.Good
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