Mixed
Dietary polyphenols (curcumin, quercetin, catechins) ameliorate metabolic disorders by being metabolized by gut microbiota into bioactive phenolic metabolites, which in turn modulate gut microbiota composition to favor beneficial bacteria and reduce pathogenic ones.
To get metabolic benefits from polyphenols like curcumin, quercetin, and catechins, focus on consistent dietary intake rather than expecting immediate high absorption. Your gut bacteria will process these compounds into active metabolites that help regulate inflammation and metabolic health. Diversity in your diet supports the microbial diversity needed for this conversion.
Studies are suggesting that ingestion of PPs might be helpful to ameliorate metabolic syndromes... Intestinal microbiota transforms PPs into their metabolites to make them bioactive. Interestingly, not only GM act on PPs to metabolize them but PPs also modulate the composition of GM.
Why this rating
This is a review paper summarizing multiple animal and human studies; specific clinical trial data is cited but not pooled in a single meta-analysis within this text.
Source
Curcumin, Quercetin, Catechins and Metabolic Diseases: The Role of Gut Microbiota
Umair Shabbir et al. · Nutrients · 2021
DOI 10.3390/nu13010206
More from this paper
- Curcumin administration improves metabolic health in obese/diabetic models by modulating gut microbiota to reduce inflammation and improve intestinal barrier function.Moderate
- Quercetin supplementation reduces inflammation and improves metabolic parameters (glucose, lipids) by modulating gut microbiota composition, specifically by increasing beneficial bacteria and reducing pathogenic ones.Moderate
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