Research
Hormonal
Fucoxanthin improves insulin sensitivity and reduces blood glucose levels by down-regulating pro-inflammatory adipokines (TNF-α, MCP-1, IL-6) and regulating lipid metabolism enzymes.
Fucoxanthin may help manage blood sugar and insulin resistance by reducing inflammation in fat tissue and regulating enzymes involved in fat synthesis. This supports metabolic health, particularly for those with insulin resistance.
ModerateSupportsMEDIUM confidence
Fucoxanthin improved insulin resistance and decreased blood glucose level, at least in part, through down-regulating adipokines, tumor necrosis factor-α, monocyte chemoattractant protein-1, interleukin-6, and plasminogen activator inhibitor-1... Fucoxanthin beneficially affects gene expression associated with lipid metabolism: in rats its supplementation decreased mRNA expression of hepatic Acetyl-CoA carboxylase (ACC)... decreased mRNA expression of fatty acid synthase (FAS)... increased... carnitine palmitoyl-transferase (CPT1).
Why this rating
Based on animal models and mechanistic reviews; human data is limited.
Source
Anti-Obesity Activity of the Marine Carotenoid Fucoxanthin
Maria Alessandra Gammone et al. · Marine Drugs · 2015
DOI 10.3390/md13042196
narrative_reviewCited 315×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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