Energy balance
Fucoxanthin supplementation induces uncoupling protein 1 (UCP1) expression in white adipose tissue, stimulating adaptive thermogenesis and increasing resting energy expenditure to promote weight loss.
To leverage fucoxanthin for weight loss, aim for a daily dose of 4-8 mg, potentially sourced from brown seaweed extracts. This intervention works by increasing your resting energy expenditure through thermogenesis, meaning you burn more calories at rest. While not a magic bullet, it supports weight loss efforts by enhancing metabolic rate.
Fucoxanthin augments the amount of energy, which is released as heat in fat tissue, thus stimulating thermogenesis... Fucoxanthin was found to promote not only UCP1 protein and mRNA expression in WAT of obese animals but also β3-adrenergic receptor (Adrb3)... Fucoxanthin supplementation was also tested in humans for weight loss: a 16-week supplementation with 4.0 mg/day showed an important increase in resting energy expenditure (REE)... This augmented REE resulted to be even more important at a dose of 8 mg.
Why this rating
The paper is a review citing multiple animal studies and a small human trial; evidence is supportive but not definitive for general population application.
Source
Anti-Obesity Activity of the Marine Carotenoid Fucoxanthin
Maria Alessandra Gammone et al. · Marine Drugs · 2015
DOI 10.3390/md13042196
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