Research
Mixed
FMT from lean donors successfully engrafts donor-specific bacteria in the majority of obese recipients, with effects persisting for at least 12 weeks, although the degree of engraftment varies significantly by donor.
FMT from lean donors can successfully introduce new bacteria into your gut, and these changes can last for months. However, this microbial change alone does not guarantee improvements in insulin sensitivity or weight loss.
GoodSupportsHIGH confidence
We observed variable engraftment of donor bacterial groups among FMT recipients, which persisted throughout the 12-week study.
Why this rating
Supported by 16S V4 sequencing and shotgun metagenomics in a controlled trial.
Source
Fecal microbiota transplantation for the improvement of metabolism in obesity: The FMT-TRIM double-blind placebo-controlled pilot trial
Elaine W Yu et al. · PLoS Medicine · 2020
DOI 10.1371/journal.pmed.1003051
rct · n=24Cited 312×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
Related findings · Mixed
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