Research
Micronutrients & recovery
Obesity (BMI >= 30 kg/m2) significantly blunts the response to Vitamin D3 supplementation, resulting in serum 25-(OH)D levels approximately 17.8 nmol/L lower than in normal-weight women for the same dose.
If you are obese, standard Vitamin D doses (like 800 IU) may not be enough to reach optimal blood levels. You likely need a higher dose to overcome the sequestration of Vitamin D in fat tissue. Consult your doctor for a personalized dose, as you may need significantly more than the standard recommendation.
GoodQualifiesHIGH confidence
Compared with participants with a normal body mass index (<=25 kg/m2), obese women (>=30 kg/m2) had a 25-(OH)D level that was 17.8 nmol/L lower.
Why this rating
Derived from the same high-quality RCT, specifically analyzed via post-hoc mixed-effects models.
Source
Dose Response to Vitamin D Supplementation in Postmenopausal Women
John C. Gallagher et al. · Annals of Internal Medicine · 2012
rct · n=163Cited 307×
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