Hormonal
Low birth weight (≤2.5 kg) is associated with higher adult fasting glucose, insulin, HOMA, and diabetes prevalence in women, and higher leptin levels and leptin-to-fat-mass ratio in both genders.
If you were born with low birth weight, you may have higher baseline leptin levels and insulin resistance compared to those born with normal weight, even if you are not overweight. This increases your risk for type 2 diabetes and cardiovascular disease. Focus on maintaining a healthy weight, regular physical activity, and monitoring blood sugar levels, as your body may be more sensitive to insulin resistance.
Women with low birth weight (≤2.5 kg) had higher levels of fasting plasma glucose, insulin, HOMA, diabetes and metabolic syndrome... In both genders... an inverse association was found between leptin and birth weight categories... An inverse association was also found between reported birth weight and leptin to fat mass ratio
Why this rating
Large population-based cross-sectional study (N=2546) with multivariate adjustments, though self-reported birth weight is a limitation.
Source
Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study
François R. Jornayvaz et al. · Cardiovascular Diabetology · 2016
DOI 10.1186/s12933-016-0389-2
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