Research
Hormonal
Adiponectin levels do not differ between birth weight groups in middle-aged adults, suggesting adiponectin does not mediate the link between birth weight and obesity/diabetes risk.
Unlike leptin, adiponectin levels do not appear to be influenced by birth weight in middle-aged adults. Therefore, strategies to improve metabolic health should not focus on manipulating adiponectin levels based on birth weight history.
GoodRefutesHIGH confidence
No differences in adiponectin levels were found between birth weight groups.
Why this rating
Large population-based study with consistent findings across genders.
Source
Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study
François R. Jornayvaz et al. · Cardiovascular Diabetology · 2016
DOI 10.1186/s12933-016-0389-2
cross_sectional · n=2546Cited 307×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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