Research
Hormonal
Women have higher insulin sensitivity but lower muscle mitochondrial ATP production rates compared to men.
Women may have a metabolic advantage in insulin sensitivity compared to men, despite having lower mitochondrial ATP production rates. This suggests that metabolic health cannot be judged solely by mitochondrial capacity or muscle mass.
GoodQualifiesHIGH confidence
Of interest, a higher mitochondrial ATP production capacity was noted in the men, whereas the women were more insulin sensitive, demonstrating further dissociation between insulin sensitivity and muscle mitochondrial function.
Why this rating
Gold standard measurement of insulin sensitivity and mitochondrial function.
Source
Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function
Helen Karakelides et al. · Diabetes · 2009
DOI 10.2337/db09-0591
cross_sectional · n=48Cited 306×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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