Research

Adherence

Regular physical activity is the most effective lifestyle-behavioral strategy for preserving physiological function with aging, delaying the onset of frailty by up to 30 years compared to sedentary peers.

Prioritize regular physical activity, even if you have been sedentary. Moderate exercise (e.g., 150 minutes/week) significantly impacts life expectancy and can restore health profiles similar to those who were active young. Focus on maintaining muscle strength and cardiorespiratory fitness to delay frailty.

StrongSupportsHIGH confidence
Regular physical activity is perhaps the lifestyle-behavioral strategy for which there is the strongest overall evidence of function-preserving effects with aging.
Douglas R. Seals et al. · The Journal of Physiology · 2015

Why this rating

Supported by cross-sectional, longitudinal, and randomized clinical trials in humans.

Source

Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity

Douglas R. Seals et al. · The Journal of Physiology · 2015

narrative_reviewCited 306×
Read the paper

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →