Energy balance
Bariatric surgery is associated with a higher rate of adverse events compared to non-surgical treatment, although early complications are often benign and long-term complications may be fewer in surgical groups.
Bariatric surgery is associated with a higher rate of adverse events compared to medical management, but these are often early and benign. Long-term, surgery may reduce the risk of serious diabetes-related complications. Patients should weigh the higher short-term risk of surgery against the potential long-term benefits of reduced complications and improved metabolic health.
Our outcome was prone to a higher adverse events rate in bariatric surgery compared with non-surgical treatment for T2DM (RR = 2.08, 95%CI: 1.53 to 2.81, P < 0.00001)... However, early surgical complications were relatively benign. There were no perioperative deaths and no late surgical complications in bariatric surgical groups after 1-year follow-up.
Why this rating
Meta-analysis of 8 RCTs, with consistent reporting of adverse events.
Source
Meta-analysis of bariatric surgery versus non-surgical treatment for type 2 diabetes mellitus
Guozhong Wu et al. · Oncotarget · 2016
DOI 10.18632/oncotarget.11961
More from this paper
- Bariatric surgery (Roux-en-Y gastric bypass, sleeve gastrectomy, or gastric banding) significantly improves Type 2 Diabetes (T2DM) remission rates, glycemic control (HbA1c, fasting plasma glucose), and weight loss compared to non-surgical medical management.Good
- Bariatric surgery leads to greater improvements in lipid profiles (increased HDL, decreased triglycerides) compared to non-surgical treatment, while LDL and total cholesterol changes are not significantly different.Good
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
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