Micronutrients & recovery
High intake of long-chain n-3 (LCn3) omega-3 fatty acids does not significantly reduce all-cause mortality, cardiovascular mortality, or major cardiovascular events compared to low intake in primary or secondary prevention populations.
If you are trying to prevent heart disease or have existing heart conditions, increasing your intake of long-chain omega-3 fatty acids (from fish or supplements) is unlikely to significantly lower your risk of death or heart events on its own. Focus on proven strategies like managing blood pressure, cholesterol, and blood sugar, and maintaining a healthy weight.
High compared with low LCn3 intake probably makes little or no difference to all-cause mortality (risk ratio (RR) 0.97, 95% confidence interval (CI) 0.93 to 1.01; 14 studies, 128,606 participants; moderate-quality evidence), cardiovascular mortality (RR 0.95, 95% CI 0.88 to 1.03; 13 studies, 127,999 participants; moderate-quality evidence), or cardiovascular events (RR 0.95, 95% CI 0.90 to 1.01; 14 studies, 128,606 participants; moderate-quality evidence).
Why this rating
Moderate-quality evidence based on large randomized controlled trials, but with some inconsistency and imprecision in certain subgroups.
Source
Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease
Asmaa Abdelhamid et al. · Cochrane Database of Systematic Reviews · 2020
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