Research

Energy balance

Maintaining high levels of habitual physical activity (defined as meeting or exceeding Health and Human Services recommendations of ~150 minutes/week of moderate activity) over a 20-year period significantly attenuates age-related weight gain in young adults transitioning to middle age, with a more pronounced effect in women.

To prevent age-related weight gain, aim to maintain a consistent level of physical activity equivalent to at least 150 minutes of moderate-intensity exercise per week. This study shows that maintaining this level over 20 years, particularly for women, significantly reduces the amount of weight gained as you transition from young adulthood to middle age. While men may experience some compensatory increase in appetite, the net effect of maintaining this activity level is still a substantial reduction in weight gain compared to being sedentary.

GoodSupportsHIGH confidence
Maintaining high activity levels through young adulthood may lessen weight gain as young adults transition to middle age, particularly in women.
Arlene Hankinson et al. · JAMA · 2010

Why this rating

Longitudinal prospective cohort study (CARDIA) with 20-year follow-up, large sample size (n=3554), and adjustment for multiple confounders, though it relies on self-reported activity.

Source

Maintaining a High Physical Activity Level Over 20 Years and Weight Gain

Arlene Hankinson et al. · JAMA · 2010

DOI 10.1001/jama.2010.1843

cohort · n=3554Cited 288×
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DOI resolved against Crossref · corpus check 2026-06-10

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