Research
Micronutrients & recovery
Preconception folic acid and multivitamin supplementation significantly reduce the risk of congenital heart defects and preeclampsia.
Taking a multivitamin with folic acid before pregnancy can lower your risk of heart defects in the baby and preeclampsia. While food is important, supplements ensure you get adequate levels during the critical early weeks.
GoodSupportsMEDIUM confidence
Pooling of two randomized trials, one cohort and one case-control trial showed a risk reduction of 42% in this analysis [congenital heart defects]... Pooling two cohort studies, the review also found a significant 27% reduction in the risk of preeclampsia... by maternal periconceptional multivitamin supplementation.
Why this rating
Based on pooled observational and experimental studies, though heterogeneity exists.
Source
Preconception care: nutritional risks and interventions
Sohni V Dean et al. · Reproductive Health · 2014
Meta-analysis · 146 studiesCited 282×
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