Energy balance
Skeletal Muscle Mass (SMM) and Appendicular Lean Soft Tissue (ALST) are critical protective factors against frailty, diabetes, and mortality, and their loss (sarcopenia) is an independent risk factor for adverse health outcomes.
Prioritize resistance training to build and maintain muscle mass, especially as you age. Muscle is not just for aesthetics; it is your primary organ for glucose disposal and metabolic health. If you are losing weight, ensure you are doing resistance training and consuming adequate protein to prevent muscle loss, which can lead to frailty and weight regain.
Loss of FFM is independently linked to increased risk of all-cause, CVD, and cancer mortality... Low SM is associated with adverse outcomes at all ages...
Why this rating
Supported by numerous studies on sarcopenia, diabetes, and mortality cited in the review.
Source
The Critical Role of Body Composition Assessment in Advancing Research and Clinical Health Risk Assessment across the Lifespan
Jonathan P. Bennett et al. · Journal of Obesity & Metabolic Syndrome · 2025
DOI 10.7570/jomes25010
More from this paper
- Body composition assessment (quantifying fat-free mass, fat mass, and visceral adipose tissue) provides a more accurate assessment of cardiometabolic disease risk than Body Mass Index (BMI) alone, particularly for identifying 'normal weight obesity' and sarcopenic obesity.Good
- Visceral Adipose Tissue (VAT) is a stronger predictor of metabolic syndrome and cardiovascular disease risk than total fat mass or BMI, particularly in Asian populations where VAT accumulation occurs at lower BMI thresholds.Good
Related findings · Energy balance
- Achieving a total body weight loss of 10-15% (or >10-15 kg) through Total Diet Replacement (TDR) induces remission of Type 2 Diabetes in individuals with short-duration disease.Strong
- Bariatric surgery is superior to medical management alone for inducing significant long-term weight loss, remission of type 2 diabetes, and reduction in mortality for patients with BMI ≥ 40 or ≥ 35 with comorbidities.Strong
- Achieving type 2 diabetes remission requires significant weight loss (≥15 kg) via major caloric restriction, independent of macronutrient composition.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →