Mixed
Regular exercise training in older adults largely negates the age-associated decline in skeletal muscle mitochondrial capacity, thereby preserving muscle health, insulin sensitivity, and physical function.
If you are an older adult, regular exercise training can significantly improve your muscle's energy production (mitochondrial capacity), insulin sensitivity, and physical performance, effectively counteracting many negative effects of aging. Focus on consistent physical activity rather than accepting decline as inevitable.
Our data also suggest that a further increase in physical activity level, achieved through regular exercise training, can largely negate the effects of aging.
Why this rating
High-quality human study with detailed phenotyping, controlled for habitual physical activity, comparing young, older, trained older, and impaired older adults.
Source
Impact of aging and exercise on skeletal muscle mitochondrial capacity, energy metabolism, and physical function
Lotte Grevendonk et al. · Nature Communications · 2021
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