Micronutrients & recovery
Repeated bouts of eccentric exercise induce cellular adaptations that attenuate serum creatine kinase (CK) release and force deficits in subsequent bouts, while simultaneously increasing the activity of the ubiquitin-proteasome proteolytic pathway.
If you perform heavy eccentric exercises (like lowering weights slowly), your body adapts to the stress. The second time you do the same workout, you will experience less muscle damage (lower enzyme leakage into blood) and recover strength faster. This adaptation is driven by your body increasing the efficiency of its internal protein recycling systems (ubiquitin-proteasome pathway).
We conclude that adaptations to eccentric exercise are associated with attenuated serum CK activity and, potentially, an increase in the activity of the ubiquitin proteosome proteolytic pathway.
Why this rating
Controlled human study with biopsy data, though sample size is small (n=16) and gender differences complicate the generalizability of inflammatory markers.
Source
Cellular adaptation to repeated eccentric exercise-induced muscle damage
Nicole Stupka et al. · Journal of Applied Physiology · 2001
DOI 10.1152/jappl.2001.91.4.1669
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