Hormonal
Natural therapeutic products, including non-flavonoid polyphenols, flavonoids, and specific plant-derived foods, serve as safer alternatives or synergistic combination therapies for Type 2 Diabetes Mellitus (T2DM) by improving insulin sensitivity, reducing oxidative stress, and ameliorating complications with fewer side effects than synthetic pharmaceuticals.
Incorporate natural therapeutic products like polyphenols (resveratrol, curcumin) and flavonoids (quercetin, anthocyanins) from sources such as berries, tea, and olive oil into your diet. These can help improve insulin sensitivity and reduce oxidative stress. They are particularly useful as a safer alternative or in combination with standard pharmaceutical treatments, especially in advanced T2DM, to enhance overall treatment efficiency and reduce side effects.
Natural health substances including non-flavonoid polyphenols (e.g., resveratrol, curcumin, tannins, and lignans), flavonoids (e.g., anthocyanins, epigallocatechin gallate, quercetin, naringin, rutin, and kaempferol), plant fruits, vegetables and other products (e.g., garlic, green tea, blackcurrant, rowanberry, bilberry, strawberry, cornelian cherry, olive oil, sesame oil, and carrot) may be a safer alternative to primary pharmacological therapy. They are recommended as food supplements to prevent and/or ameliorate T2DM-related complications. In the advanced stage of T2DM, the combination therapy of synthetic agents and natural compounds with synergistic interactions makes the treatment more efficient.
Why this rating
The paper is a review summarizing various studies, including in vitro, animal, and some human trials, but lacks a single definitive large-scale clinical trial.
Source
Pharmaceutical Drugs and Natural Therapeutic Products for the Treatment of Type 2 Diabetes Mellitus
Jana Bláhová et al. · Pharmaceuticals · 2021
DOI 10.3390/ph14080806
More from this paper
- Specific natural compounds, such as resveratrol, curcumin, and honey, improve glucose control and insulin sensitivity through mechanisms like activating sirtuins, inhibiting alpha-amylase, and reducing oxidative stress in pancreatic beta-cells.Moderate
- Pharmaceutical drugs for T2DM, while effective, are associated with harmful side effects, making natural therapeutic products a preferred option for prevention and early-stage management.Moderate
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