Research
Hormonal
Women have higher skeletal muscle lipoprotein lipase (mLPL) mRNA expression and higher plasma triglyceride clearance compared to men, facilitating greater lipid storage in muscle.
Women's bodies are biologically designed to clear fats from the blood into muscle more efficiently than men's. This is why women often have lower post-meal triglyceride levels, which is a protective factor for heart health.
GoodSupportsHIGH confidence
we have reported 160% higher mRNA of mLPL in young women compared to matched males... TG extraction from plasma was demonstrated to be ~7- and ~3-fold higher in women than men
Why this rating
Based on multiple studies measuring mRNA and tracer kinetics.
Source
Gender Differences in Skeletal Muscle Substrate Metabolism – Molecular Mechanisms and Insulin Sensitivity
Anne‐Marie Lundsgaard et al. · Frontiers in Endocrinology · 2014
DOI 10.3389/fendo.2014.00195
narrative_reviewCited 272×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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