Research
Mixed
Platelet-rich plasma (PRP) injections show no significant positive effect on muscle injury recovery compared to placebo in randomized clinical trials, despite widespread clinical use.
Do not expect PRP injections to significantly improve your muscle injury recovery compared to standard care or placebo. Current clinical trials do not support its efficacy for this specific use case.
StrongRefutesHIGH confidence
Nevertheless, a recent randomized clinical trial show no significant positive effects of PRP injections, as compared with placebo injections, in patients with muscle injuries, up to one year after injections (Reurink et al. 2014; Reurink et al. 2015).
Why this rating
Based on randomized clinical trials, which are higher quality than the animal models or reviews cited for other interventions.
Source
Muscle injuries and strategies for improving their repair
Thomas Laumonier et al. · Journal of Experimental Orthopaedics · 2016
DOI 10.1186/s40634-016-0051-7
narrative_reviewCited 272×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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