Research

Micronutrients & recovery

High total calcium intake (≥1400 mg/day) is associated with significantly higher rates of all-cause and cardiovascular mortality in women, particularly when combined with calcium supplement use.

For women, maintaining total calcium intake (diet plus supplements) between 600 and 1000 mg/day appears to be associated with lower mortality risk compared to intakes above 1400 mg/day. If you are taking calcium supplements, be mindful of your total daily intake from all sources to avoid exceeding 1400 mg/day, as this may be linked to higher cardiovascular and all-cause mortality risks.

GoodRefutesHIGH confidence
Compared with intakes between 600 and 1,000 mg/day, intakes above 1400 mg/day were associated with higher death rates from all causes (hazard ratio 1.40, 95% confidence interval 1.17-1.67), cardiovascular disease (149, 1.09-2.02), and ischemic heart disease (2.14, 1.48-3.09)... Use of calcium tablets... was not on average associated with all cause or cause specific mortality but among calcium tablet users with a dietary calcium intake above 1,400 mg/day the hazard ratio for all cause mortality was 2.57
Karl Michaëlsson et al. · BMJ · 2013

Why this rating

Large prospective cohort study (n=61,433) with long follow-up (median 19 years), though observational design limits causal inference compared to RCTs.

Source

Long term calcium intake and rates of all cause and cardiovascular mortality: community based prospective longitudinal cohort study

Karl Michaëlsson et al. · BMJ · 2013

cohort · n=61433Cited 267×
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