Research
Mixed
Higher gut microbiome diversity is associated with lower levels of very-low-density lipoprotein (VLDL) particles, serum triglycerides, and total fatty acids, and higher levels of large/high-density lipoprotein (HDL) particles.
Focus on dietary patterns that support gut microbial diversity, such as high fiber intake and fermented foods, as this state is strongly linked to healthier lipid profiles (lower triglycerides, higher protective HDL).
GoodSupportsHIGH confidence
higher microbiome diversity was significantly associated with lower levels of VLDL particles (small, large, medium, very large, and extra-large), serum triglycerides, TotFA, MUFA, and SFA, and increased levels of large and extra-large HDL particles and an increased diameter of HDL
Why this rating
Large population-based cohorts (n=2309) with rigorous statistical adjustment, though the cross-sectional design limits causal inference.
Source
Relationship between gut microbiota and circulating metabolites in population-based cohorts
Dina Vojinović et al. · Nature Communications · 2019
DOI 10.1038/s41467-019-13721-1
cohort · n=2309Cited 260×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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