Research
Micronutrients & recovery
Polyunsaturated fatty acids (PUFAs) from olive oil, nuts, and seeds improve glycemic control and insulin sensitivity by stimulating GLP-1 secretion and reducing adipose inflammation.
Replace saturated and trans fats with unsaturated fats from olive oil, nuts, and seeds. This substitution can significantly reduce the risk of Type 2 Diabetes and improve insulin sensitivity, provided total fat intake remains moderate (below 37% of energy).
GoodSupportsHIGH confidence
PUFAs may ameliorate the adipose tissue’s inflammatory responses... PUFAs can bind and stimulate G-protein-coupled receptors (GPCRs)... thereby leading to increased secretion of the glucagon-like peptide 1 (GLP-1) hormone
Why this rating
Supported by animal models and meta-analyses cited.
Source
Mediterranean Diet Nutrients to Turn the Tide against Insulin Resistance and Related Diseases
Maria Mirabelli et al. · Nutrients · 2020
DOI 10.3390/nu12041066
narrative_reviewCited 256×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Adherence to a Mediterranean Diet (MedDiet) improves insulin sensitivity and glycemic control in obese individuals with type 2 diabetes or insulin resistance, independent of significant weight loss.Good
- Resveratrol supplementation (1500 mg/day) significantly decreases testosterone and dehydroepiandrosterone sulfate levels in women with Polycystic Ovary Syndrome (PCOS).Moderate
- Anthocyanins from purple fruits and vegetables improve cognitive function and reduce beta-amyloid deposition in early-onset Alzheimer's disease models via PPARγ activation.Moderate
Related findings · Micronutrients & recovery
- Trans fats (industrial trans-fatty acids) are unequivocally harmful and should be completely avoided as they raise LDL-C, TGs, and Apo B while lowering HDL-C.Strong
- For menopausal women with osteoporosis, first-line pharmacologic therapies include alendronate, risedronate, zoledronic acid, and denosumab for the prevention of hip, nonvertebral, and vertebral fractures.Strong
- Folic acid fortification of flour prevents neural tube birth defects, and mandatory fortification is more effective than voluntary supplementation alone.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →