Research

Micronutrients & recovery

Bariatric surgery alters drug absorption and bioavailability, casting doubt on the validity of standard drug dosages for medications like antidepressants, antimicrobials, and metformin.

After bariatric surgery, your body absorbs medications differently. Do not assume your current dose is correct. Talk to your doctor about adjusting dosages for antidepressants, antibiotics, or other common drugs to ensure they are effective.

GoodQualifiesHIGH confidence
Many drugs commonly administered to obese patients (e.g. anti-depressants, anti-microbials, metformin) are subject to post-operative and/or PPI-associated changes affecting bioavailability and absorption.
Jürgen M. Stein et al. · Alimentary Pharmacology & Therapeutics · 2014

Why this rating

Based on review of pharmacokinetic studies and clinical observations.

Source

Review article: the nutritional and pharmacological consequences of obesity surgery

Jürgen M. Stein et al. · Alimentary Pharmacology & Therapeutics · 2014

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