Research
Mixed
Higher circulating levels of long-chain omega-3 fatty acids are associated with lower risk of death from cardiovascular disease, cancer, and other causes.
Maintaining higher blood levels of marine omega-3s (EPA, DHA, DPA) is associated with a reduced risk of dying from heart disease, cancer, and other causes. This suggests that optimizing omega-3 status may support overall longevity beyond just heart health.
StrongSupportsHIGH confidence
Similar relationships were seen for death from cardiovascular disease, cancer and other causes.
Why this rating
Large pooled analysis with sufficient power to detect cause-specific trends.
Source
Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies
William S. Harris et al. · Nature Communications · 2021
DOI 10.1038/s41467-021-22370-2
Meta-analysis · 17 studiesCited 231×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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