Mixed
Higher relative abundance of Oscillospira members in the fecal microbiome is significantly associated with lower visceral fat mass, suggesting a protective role against cardio-metabolic risk.
Focus on reducing visceral fat through lifestyle changes, as specific gut bacteria (like Oscillospira) are strongly linked to lower visceral fat levels. While your genetics influence your baseline microbiome, the association with visceral fat suggests that managing abdominal adiposity may positively influence your gut microbial profile, potentially lowering cardio-metabolic risk.
Most of these results involve visceral fat associations, with the strongest associations between visceral fat and Oscillospira members... OTUs within Oscillospira... all showed negative associations with VFM and AGR, suggesting a potential protective role for these bacteria in cardiovascular risk
Why this rating
Large sample size (3666 twins), robust replication across three independent cohorts, and stringent statistical thresholds (Bonferroni).
Source
Heritable components of the human fecal microbiome are associated with visceral fat
Michelle Beaumont et al. · Genome biology · 2016
DOI 10.1186/s13059-016-1052-7
More from this paper
- Lower fecal microbiome alpha diversity (Shannon diversity) is significantly associated with higher visceral fat mass and overall abdominal adiposity.Good
- Host genetic variants in the FHIT, TDRG1, and ELAVL4 genes are significantly associated with the abundance of specific adiposity-linked fecal microbes, suggesting host genetics mediate the microbiome-obesity link.Moderate
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