Mixed
In dialysis patients, low muscle strength is a significant predictor of all-cause mortality, whereas low muscle mass alone is not associated with increased mortality risk when adjusted for confounders.
If you are on dialysis, focus on building functional strength (e.g., handgrip, leg press) rather than just trying to increase muscle size. Your ability to generate force is a much stronger predictor of your survival chances than how much muscle you have. Consult your care team for resistance training protocols suitable for your condition.
Individuals with low muscle strength were at increased risk, irrespective of their muscle stores being appropriate (HR, 1.98... ) or low (HR, 1.93... ). Individuals with low muscle mass alone were not at increased risk of mortality (adjusted hazard ratio [HR], 1.23; 95% confidence interval [95% CI], 0.56 to 2.67).
Why this rating
Prospective cohort study with multivariate adjustment, though observational design limits causal inference.
Source
Comparative Associations of Muscle Mass and Muscle Strength with Mortality in Dialysis Patients
Naohito Isoyama et al. · Clinical Journal of the American Society of Nephrology · 2014
DOI 10.2215/cjn.10261013
Related findings · Mixed
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