Micronutrients & recovery
The association between DHA levels and specific gut bacteria (Lachnospiraceae) may be mediated by the production of N-carbamylglutamate (NCG), a metabolite correlated with both DHA and these bacterial abundances.
The benefit of DHA on gut bacteria might involve the production of N-carbamylglutamate (NCG). While NCG is available as a supplement, this study suggests the body may produce it in response to DHA, potentially improving gut function and reducing oxidative stress.
Some of the associations with gut bacterial OTUs appear to be mediated by the abundance of the faecal metabolite N-carbamylglutamate... some of the DHA associations with these OTUs are attenuated when adjusting for NCG levels
Why this rating
The mediation is suggested by attenuation of coefficients when adjusting for NCG, but causality is not proven in this cross-sectional study.
Source
Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women
Cristina Menni et al. · Scientific Reports · 2017
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