Mixed
Financial conflicts of interest are prevalent among members of clinical practice guideline panels, with a significantly higher prevalence in non-government sponsored guidelines compared to government sponsored ones.
When evaluating clinical guidelines, check the funding source and panel disclosures. Non-government sponsored guidelines have a 69% rate of financial conflicts of interest, compared to 16% for government-sponsored ones. Prioritize guidelines with transparent, government or non-profit backing to minimize bias.
The prevalence of conflicts of interest is high among members of such clinical practice guideline panels and is significantly higher among panellists from non-government sponsored guidelines than among those from government sponsored guidelines.
Why this rating
Cross-sectional study with a reasonable sample size (288 panel members) across multiple organizations, though limited to two disease conditions.
Source
Prevalence of financial conflicts of interest among panel members producing clinical practice guidelines in Canada and United States: cross sectional study
J Neuman et al. · BMJ · 2011
DOI 10.1136/bmj.d5621
Related findings · Mixed
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