Mixed
A panel of biomarkers including physical capability (grip strength, walking speed), physiological function (blood pressure, glucose), cognitive function (executive function, processing speed), and inflammatory markers (IL-6, TNF-alpha) serves as valid surrogate endpoints for assessing healthy ageing and predicting mortality.
To track your biological health, focus on measurable functional outputs rather than just your birth year. Regularly monitor your grip strength, walking speed, blood pressure, and fasting glucose. These are established, accessible indicators that predict mortality and functional decline better than age alone. If you are maintaining or improving these metrics, you are likely ageing healthily.
We present recommendations for a panel of biomarkers that address these major areas of function which decline during ageing. This biomarker panel may have utility in epidemiological studies of human ageing... and as outcomes in intervention studies that aim to promote healthy ageing.
Why this rating
Based on comprehensive literature reviews, systematic reviews, and expert consensus, though no single universal biomarker exists.
Source
A proposed panel of biomarkers of healthy ageing
José Lara et al. · BMC Medicine · 2015
DOI 10.1186/s12916-015-0470-9
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